Request / Find a Test Tool

The National Genomic Test Directories specify which genomic tests are commissioned by the NHS in England, to be delivered by Genomic Laboratory Hubs.

This tool allows clinical teams to search all of the genomic tests available to patients through the National Testing Directory. From here you can find out more details about each test and information about how to order them. These tests can only be ordered by clinical teams, if you are a patient looking to request a test please speak to your clinical team directly.

Autoinflammatory Disorders

Clinical Indication ID & Name


Autoinflammatory Disorders

Test Group


Test code


Test name


Target genes

Autoinflammatory disorders (1075)

Test scope


Test method/ technology

WES or Medium panel

Optimal Family Structure


Eligibility Criteria

1. Evidence of recurrent or continuous inflammation ( localised or systemic) of otherwise undetermined cause, which fluctuate apparently randomly, either periodically or irregularly AND
2. Infectious and autoimmune testing will have been non-diagnostic.

Attacks typically start during childhood but symptoms can also begin during adolescence or even in later adulthood. Main symptom is fever. Other symptoms include serositis (peritonitis, pleuritis and pericarditis), recurrent stroke-like episodes, myalgia, arthralgia and rash, CNS, gastrointestinal and respiratory symptoms.

Commissioning group

Highly Specialised

Overlapping idications

• R15 Primary immunodeficiency or monogenic Inflammatory Bowel Disease

Address for samples/request forms

North Thames GLH, Rare & Inherited Disease Genomic Laboratory
Specimen Reception, Level 5 Barclay House, 37 Queen Square,
London WC1N 3BH

Contact with queries

Supporting documents


Education resources


Service updates


Request form download

Consent record

See consent guidance in test request form

Sample requirements

See sample guidance in test request form