Request / Find a Test Tool

The National Genomic Test Directories specify which genomic tests are commissioned by the NHS in England, to be delivered by Genomic Laboratory Hubs.

This tool allows clinical teams to search all of the genomic tests available to patients through the National Testing Directory. From here you can find out more details about each test and information about how to order them. These tests can only be ordered by clinical teams, if you are a patient looking to request a test please speak to your clinical team directly.

Y chromosome microdeletion

Clinical Indication ID & Name


Y chromosome microdeletion

Test Group


Test code


Test name


Target genes

Y chromosome AZF regions

Test scope


Test method/ technology

Targeted mutation testing or equivalent

Optimal Family Structure


Eligibility Criteria

Patients with non-obstructive azoospermia or severe oligospermia where testicular sperm extraction (TESE)/microdissection TESE (mTESE) is considered and outcome of testing will inform eligibility for (m)TESE and success of sperm retrieval (

Testing for Y chromosome microdeletions should not routinely be performed before ICSI

Testing for this clinical indication is performed by designated GLHs on behalf of the national genomic testing network

Commissioning group


Overlapping idications

• R298 - Possible structural or mosaic chromosomal abnormality requiring FISH

Address for samples/request forms

North Thames GLH, Rare & Inherited Disease Genomic Laboratory
Specimen Reception, Level 5 Barclay House, 37 Queen Square,
London WC1N 3BH

Contact with queries

Supporting documents


Education resources


Service updates


Request form download

Consent record

See consent guidance in test request form

Sample requirements

See sample guidance in test request form