Clinical Indication ID & Name
Patient receiving solid organ transplantation (only in cases where passenger lymphocyte syndrome is suspected)
Test Group
Core/Specialised
Specialties
Test code
R428.1
Test name
N/A
Target genes
Relevant gene(s) or loci
Test scope
n/a
Test method/ technology
STR testing
Optimal Family Structure
n/a
Eligibility Criteria
Patient is post-solid organ transplant and the treating clinician has concerns they have developed passenger lymphocyte syndrome based on their clinical presentation; i.e. they have developed cytopenias not wholly explainable via other causes.
Allogeneic transplant where chimerism knowledge will aid patient management.
Test code
R428.2
Test name
N/A
Target genes
Sex chromosomes
Test scope
n/a
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Patient is post-solid organ transplant and the treating clinician has concerns they have developed passenger lymphocyte syndrome based on their clinical presentation; i.e. they have developed cytopenias not wholly explainable via other causes.
Allogeneic transplant where chimerism knowledge will aid patient management.
Commissioning group
Core/Specialised
Overlapping idications
• M242 Any patient receiving solid organ transplantation – same test duplicated in the cancer Test Directory
Address for samples/request forms
North Thames GLH, Rare & Inherited Disease Genomic Laboratory
Specimen Reception, Level 5 Barclay House, 37 Queen Square,
London WC1N 3BH
Contact with queries
Supporting documents
n/a
Education resources
n/a
Service updates
n/a
Request form download
Consent record
See consent guidance in test request form
Sample requirements
See sample guidance in test request form