Clinical Indication ID & Name
M236
Oesophageal Cancer
Test Group
Solid Tumours (Adult)
Specialties
Test code
M236.1
Test name
MSI Testing
Target genes
N/A
Test scope
Microsatellite instability analysis
Test method/ technology
Microsatellite instability analysis
Optimal Family Structure
n/a
Eligibility Criteria
Known oesophageal cancer, when MMR IHC not possible / not performed, as per NICE Guidelines for molecular testing to inform therapy choice. Delivery via pathology in some regions.
Test code
M236.2
Test name
DPYD hotspot
Target genes
DPYD
Test scope
Small variant detection
Test method/ technology
Simple targeted mutation testing
Optimal Family Structure
n/a
Eligibility Criteria
Patient planned to receive fluoropyrimidine treatment
Commissioning group
n/a
Overlapping idications
n/a
Address for samples/request forms
North Thames GLH, Rare & Inherited Disease Genomic Laboratory
Specimen Reception, Level 5 Barclay House, 37 Queen Square,
London WC1N 3BH
Contact with queries
Supporting documents
n/a
Education resources
n/a
Service updates
n/a
Request form download
Consent record
See consent guidance in test request form
Sample requirements
See sample guidance in test request form