Clinical Indication ID & Name
Malt-Lymphoma
Test Group
Haematology
Specialties
Test code
M107.1
Test name
t(11;18)(q21;q21) BIRC3-MALT1 FISH/RT-PCR
Target genes
BIRC3-MALT1
Test scope
Structural variant detection
Test method/ technology
FISH/Simple targeted mutation testing
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M107.2
Test name
t(1;14)(p22;q32) IGH-BCL10 FISH/RT-PCR
Target genes
IGH-BCL10
Test scope
Structural variant detection
Test method/ technology
FISH/Simple targeted mutation testing
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M107.3
Test name
t(14;18)(q32;q21) IGH-MALT1 FISH/RT-PCR
Target genes
IGH-MALT1
Test scope
Structural variant detection
Test method/ technology
FISH/Simple targeted mutation testing
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M107.4
Test name
MALT1 rearrangement FISH
Target genes
MALT1
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M107.5
Test name
BCL10 rearrangement FISH
Target genes
BCL10
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M107.6
Test name
FOXP1 rearrangement FISH
Target genes
FOXP1
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M107.7
Test name
WGS Germline and Tumour
Target genes
All including burden / signature
Test scope
All variant types
Test method/ technology
WGS
Optimal Family Structure
n/a
Eligibility Criteria
For paediatric patients only
Test code
M107.8
Test name
Multi-target NGS panel - structural variant (BIRC3-MALT1, IGH-BCL10, IGH-MALT1, other MALT rearrangements, other BCL10 rearrangements, FOXP1)
Target genes
BIRC3-MALT1, IGH-BCL10, IGH-MALT1, MALT1, BCL10, FOXP1
Test scope
Structural variant detection
Test method/ technology
Panel
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Commissioning group
n/a
Overlapping idications
n/a
Address for samples/request forms
North Thames GLH, Rare & Inherited Disease Genomic Laboratory
Specimen Reception, Level 5 Barclay House, 37 Queen Square,
London WC1N 3BH
Contact with queries
Supporting documents
n/a
Education resources
n/a
Service updates
n/a
Request form download
n/a
Consent record
See consent guidance in test request form
Sample requirements
See sample guidance in test request form