Clinical Indication ID & Name
Acute Lymphoblastic Leukaemia
Test Group
Haematology
Specialties
Test code
M91.1
Test name
WGS Germline and Tumour
Target genes
All including burden / signature
Test scope
All variant types
Test method/ technology
WGS
Optimal Family Structure
n/a
Eligibility Criteria
Both adult and paediatric patients with ALL are eligible for WGS
Test code
M91.2
Test name
Karyotype (To include detection of complex karyotype, hyperdiploidy, high hyperdiploidy, near haploidy, low hypodiploidy, del(1)(p33p33), iAMP21, copy number changes of IKZF1, CDKN2A, CDKN2B, BTG1, EBF1, PAX5, RB1, PAR1 region (CRLF2, CSF2RA, IL3RA) , ETV6 & t(9;22)(q34:q11) BCR-ABL1, t(12;21)(p13;q22) ETV6-RUNX1, t(1;19)(q23;p13) TCF3-PBX1, t(17;19)(q22;p13) TCF3-HLF, t(4;11)(q21;q23) KMT2A-AFF1, t(11;19)(q23;p13.3) KMT2A-MLLT1, t(6;11)(q27;q23) KMT2A-AFDN, t(9;11)(p21;q23) KMT2A-MLLT3, t(10;11)(p12;q23) KMT2A-MLLT10, t(11;19)(q23;p13.1) KMT2A-ELL, t(1;7)(p32;q11) TRB-TAL1, t(11;14)(p15;q11) TRD-LMO1, t(7;11)(p15;p15) NUP98-HOXA13, t(10;14)(q24;q11) TLX1-TRD, t(7;10)(q34;q24) TRB-TLX1, t(5;14)(q35;q32.2) BCL11B-TLX3, rearrangements of TAL1, TLX1, TLX3, PDGFRA, PDGFRB, ABL1, JAK2, KMT2A, ABL2, CSF1R, 14Q32, CRLF2, EPOR)
Target genes
To include detection of complex karyotype, hyperdiploidy, high hyperdiploidy, near haploidy, low hypodiploidy, del(1)(p33p33), iAMP21, copy number changes of IKZF1, CDKN2A, CDKN2B, BTG1, EBF1, PAX5, RB1, PAR1 region (CRLF2, CSF2RA, IL3RA) , ETV6 & t(9;22)(q34:q11) BCR-ABL1, t(12;21)(p13;q22) ETV6-RUNX1, t(1;19)(q23;p13) TCF3-PBX1, t(17;19)(q22;p13) TCF3-HLF, t(4;11)(q21;q23) KMT2A-AFF1, t(11;19)(q23;p13.3) KMT2A-MLLT1, t(6;11)(q27;q23) KMT2A-AFDN, t(9;11)(p21;q23) KMT2A-MLLT3, t(10;11)(p12;q23) KMT2A-MLLT10, t(11;19)(q23;p13.1) KMT2A-ELL, t(1;7)(p32;q11) TRB-TAL1, t(11;14)(p15;q11) TRD-LMO1, t(7;11)(p15;p15) NUP98-HOXA13, t(10;14)(q24;q11) TLX1-TRD, t(7;10)(q34;q24) TRB-TLX1, t(5;14)(q35;q32.2) BCL11B-TLX3, rearrangements of TAL1, TLX1, TLX3, PDGFRA, PDGFRB, ABL1, JAK2, KMT2A, ABL2, CSF1R, 14Q32, CRLF2, EPOR
Test scope
Copy number variant detection to genomewide resolution; Structural variant detection
Test method/ technology
Karyotype or equivalent i.e. SNP array
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.4
Test name
FISH copy number and rearrangement other: See tests M91.24-M91.62 for individual specified FISH targets.
Target genes
Other: See tests M91.24-M91.62 for individual specified FISH targets.
Test scope
Copy number variant detection to genomewide resolution; Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.6
Test name
Other RT-PCR: See tests M91-63-M91.77 for individual specified RT-PCR targets
Target genes
Other : See tests M91-63-M91.77 for individual specified RT-PCR targets
Test scope
Structural variant detection
Test method/ technology
RT-PCR
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.7
Test name
Multi-target NGS panel - structural variant. To include: BCR-ABL1, t(12;21)(p13;q22) ETV6-RUNX1, t(1;19)(q23;p13) TCF3-PBX1, t(17;19)(q22;p13) TCF3-HLF, t(4;11)(q21;q23) KMT2A-AFF1, t(11;19)(q23;p13.3) KMT2A-MLLT1, t(6;11)(q27;q23) KMT2A-AFDN, t(9;11)(p21;q23) KMT2A-MLLT3, t(10;11)(p12;q23) KMT2A-MLLT10, t(11;19)(q23;p13.1) KMT2A-ELL, t(1;7)(p32;q11) TRB-TAL1, t(11;14)(p15;q11) TRD-LMO1, t(7;11)(p15;p15) NUP98-HOXA13, t(10;14)(q24;q11) TLX1-TRD, t(7;10)(q34;q24) TRB-TLX1, t(5;14)(q35;q32.2) BCL11B-TLX3, rearrangements of TAL1, TLX1, TLX3, PDGFRA, PDGFRB, ABL1, JAK2, KMT2A, ABL2, CSF1R, 14Q32, CRLF2, EPOR)
Target genes
To include: BCR-ABL1, ETV6-RUNX1, TCF3-PBX1, TCF3-HLF, KMT2A-AFF1, KMT2A-MLLT1, KMT2A-AFDN, KMT2A-MLLT3, KMT2A-MLLT10, KMT2A-ELL, TRB-TAL1, TRD-LMO1, NUP98-HOXA13, TLX1-TRD, TRB-TLX1, BCL11B-TLX3, rearrangements of TAL1, TLX1, TLX3, PDGFRA, PDGFRB, ABL1, JAK2, KMT2A, ABL2, CSF1R, 14Q32, CRLF2, EPOR)
Test scope
Structural variant detection
Test method/ technology
Panel
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.8
Test name
BCR-ABL1 multiplex
Target genes
BCR-ABL1
Test scope
Structural variant detection
Test method/ technology
Simple targeted mutation testing
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.9
Test name
MRD BCR-ABL1 RT-qPCR
Target genes
BCR-ABL1 p190 & BCR-ABL1 p210
Test scope
Structural variant detection
Test method/ technology
QF-PCR or equivalent
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.10
Test name
BCR-ABL1 FISH
Target genes
BCR-ABL1
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.11
Test name
BCR-ABL1 TKD NGS
Target genes
BCR-ABL1
Test scope
Small variant detection
Test method/ technology
Panel
Optimal Family Structure
n/a
Eligibility Criteria
Known ALL with BCR-ABL1 translocation, clinically thought to have BCR-ABL1 TKD mutations
Test code
M91.13
Test name
BCR-ABL1 T315I seq
Target genes
BCR-ABL1
Test scope
Small variant detection
Test method/ technology
Simple targeted mutation testing
Optimal Family Structure
n/a
Eligibility Criteria
Known ALL with BCR-ABL1 translocation, clinically thought to have BCR-ABL1 TKD mutations
Test code
M91.14
Test name
MRD ALL RT-qPCR
Target genes
Can include detection t(9;22)(q34:q11) BCR-ABL1, t(12;21)(p13;q22) ETV6-RUNX1, t(1;19)(q23;p13) TCF3-PBX1, t(17;19)(q22;p13) TCF3-HLF, t(4;11)(q21;q23) KMT2A-AFF1, t(11;19)(q23;p13.3) KMT2A-MLLT1, t(6;11)(q27;q23) KMT2A-AFDN, t(9;11)(p21;q23) KMT2A-MLLT3,
Test scope
Structural variant detection
Test method/ technology
QF-PCR or equivalent
Optimal Family Structure
n/a
Eligibility Criteria
ALL with known translocation which can be detected with sufficient sensitivity using a PCR-based technique that it can be used for MRD monitoring
Test code
M91.15
Test name
Multi-target NGS panel - small variant (ETV6, NOTCH1, FBXW7, TP53, PTEN, KRAS, NRAS, HRAS, IKZF1)
Target genes
ETV6, NOTCH1, FBXW7, TP53, PTEN, KRAS, NRAS, HRAS, IKZF1
Test scope
Small variant detection
Test method/ technology
Panel
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.22
Test name
MRD target identification (Ig/TCR gene rearrangement by PCR & sequencing with MRD workup via QF-PCR)
Target genes
IGH, IGK, IGL, (TRA), TRB, TRG, TCRD
Test scope
Complex variant detection
Test method/ technology
Multiple
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.23
Test name
MRD quantification (Ig/TCR gene rearrangement MRD QF-PCR )
Target genes
IGH, IGK, IGL, (TRA), TRB, TRG, TCRD
Test scope
Complex variant detection
Test method/ technology
Complex targeted mutation testing
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.24
Test name
Global copy number change FISH (i.e. hyperdiploidy, high hyperdiploidy, near haploidy, low hypodiploidy)
Target genes
Multiple chromosomes
Test scope
Copy number variant detection to genomewide resolution
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.25
Test name
del(1)(p33p33) FISH
Target genes
TAL1
Test scope
Copy number variant detection to genomewide resolution
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.26
Test name
iAMP21 FISH
Target genes
RUNX1
Test scope
Copy number variant detection to genomewide resolution
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.36
Test name
t(12;21)(p13;q22) ETV6-RUNX1 FISH
Target genes
ETV6-RUNX1
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.37
Test name
t(1;19)(q23;p13) TCF3-PBX1 FISH
Target genes
TCF3-PBX1
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.38
Test name
t(17;19)(q22;p13) TCF3-HLF FISH
Target genes
TCF3-HLF
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.39
Test name
t(4;11)(q21;q23) KMT2A-AFF1 FISH
Target genes
KMT2A-AFF1
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.40
Test name
t(11;19)(q23;p13.3) KMT2A-MLLT1 FISH
Target genes
KMT2A-MLLT1
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.41
Test name
t(6;11)(q27;q23) KMT2A-AFDN FISH
Target genes
KMT2A-AFDN
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.42
Test name
t(9;11)(p21;q23) KMT2A-MLLT3 FISH
Target genes
KMT2A-MLLT3
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.43
Test name
t(10;11)(p12;q23) KMT2A-MLLT10 FISH
Target genes
KMT2A-MLLT10
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.44
Test name
t(11;19)(q23;p13.1) KMT2A-ELL FISH
Target genes
KMT2A-ELL
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.45
Test name
t(1;7)(p32;q11) TRB-TAL1 FISH
Target genes
TRB-TAL1
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.46
Test name
t(11;14)(p15;q11) TRD-LMO1 FISH
Target genes
TRD-LMO1
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.47
Test name
t(7;11)(p15;p15) NUP98-HOXA13 FISH
Target genes
NUP98-HOXA13
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.48
Test name
t(10;14)(q24;q11) TLX1-TRD FISH
Target genes
TLX1-TRD
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.49
Test name
t(7;10)(q34;q24) TRB-TLX1 FISH
Target genes
TRB-TLX1
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.50
Test name
t(5;14)(q35;q32.2) BCL11B-TLX3 FISH
Target genes
BCL11B-TLX3
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.51
Test name
TAL1 rearrangement FISH (other than TRB-TAL1 see M91.45)
Target genes
TAL1
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.52
Test name
TLX1 rearrangement FISH (other than TLX1-TRD & TRB-TLX1 see M91.48 & M91.49)
Target genes
TLX1
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.54
Test name
PDGFRB rearrangement FISH
Target genes
PDGFRB
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.54
Test name
PDGFRB rearrangement FISH
Target genes
PDGFRB
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.55
Test name
ABL1 rearrangement FISH (other than BCR-ABL1 see M91.10)
Target genes
ABL1
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.56
Test name
JAK2 rearrangement FISH
Target genes
JAK2
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.57
Test name
KMT2A rearrangement FISH (other than specific rearrangements described in tests M91.30-91,44)
Target genes
KMT2A
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.58
Test name
ABL2 rearrangement FISH
Target genes
ABL2
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.59
Test name
CSF1R rearrangement FISH
Target genes
CSF1R
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.60
Test name
14q32(IGH) rearrangement FISH
Target genes
IGH
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.61
Test name
CRLF2 rearrangement FISH
Target genes
CRLF2
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.62
Test name
EPOR rearrangement FISH
Target genes
EPOR
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.63
Test name
t(12;21)(p13;q22) ETV6-RUNX1 RT-PCR
Target genes
ETV6-RUNX1
Test scope
Structural variant detection
Test method/ technology
RT-PCR
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.64
Test name
t(1;19)(q23;p13) TCF3-PBX1 RT-PCR
Target genes
TCF3-PBX1
Test scope
Structural variant detection
Test method/ technology
RT-PCR
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.65
Test name
t(17;19)(q22;p13) TCF3-HLF RT-PCR
Target genes
TCF3-HLF
Test scope
Structural variant detection
Test method/ technology
RT-PCR
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.66
Test name
t(4;11)(q21;q23) KMT2A-AFF1 RT-PCR
Target genes
KMT2A-AFF1
Test scope
Structural variant detection
Test method/ technology
RT-PCR
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.67
Test name
t(11;19)(q23;p13.3) KMT2A-MLLT1 RT-PCR
Target genes
KMT2A-MLLT1
Test scope
Structural variant detection
Test method/ technology
RT-PCR
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.68
Test name
t(6;11)(q27;q23) KMT2A-AFDN RT-PCR
Target genes
KMT2A-AFDN
Test scope
Structural variant detection
Test method/ technology
RT-PCR
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.69
Test name
t(9;11)(p21;q23) KMT2A-MLLT3 RT-PCR
Target genes
KMT2A-MLLT3
Test scope
Structural variant detection
Test method/ technology
RT-PCR
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.70
Test name
t(10;11)(p12;q23) KMT2A-MLLT10 RT-PCR
Target genes
KMT2A-MLLT10
Test scope
Structural variant detection
Test method/ technology
RT-PCR
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.71
Test name
t(11;19)(q23;p13.1) KMT2A-ELL RT-PCR
Target genes
KMT2A-ELL
Test scope
Structural variant detection
Test method/ technology
RT-PCR
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.72
Test name
t(1;7)(p32;q11) TRB-TAL1 RT-PCR
Target genes
TRB-TAL1
Test scope
Structural variant detection
Test method/ technology
RT-PCR
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.73
Test name
t(11;14)(p15;q11) TRD-LMO1 RT-PCR
Target genes
TRB-TAL1
Test scope
Structural variant detection
Test method/ technology
RT-PCR
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.74
Test name
t(7;11)(p15;p15) NUP98-HOXA13 RT-PCR
Target genes
NUP98-HOXA13
Test scope
Structural variant detection
Test method/ technology
RT-PCR
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.75
Test name
t(10;14)(q24;q11) TLX1-TRD RT-PCR
Target genes
TLX1-TRD
Test scope
Structural variant detection
Test method/ technology
RT-PCR
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.76
Test name
t(7;10)q34;q24) TRB-TLX1 RT-PCR
Target genes
TRB-TLX1
Test scope
Structural variant detection
Test method/ technology
RT-PCR
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.77
Test name
t(5;14)(q35;q32.2) BCL11B-TLX3 RT-PCR
Target genes
BCL11B-TLX3
Test scope
Structural variant detection
Test method/ technology
RT-PCR
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.78
Test name
Multi-target NGS panel - copy number variant (to include hyperdiploidy, high hyperdiploidy, near haploidy, low hypodiploidy, del(1)(p33p33), iAMP21, copy number changes of IKZF1, CDKN2A, CDKN2B, BTG1, EBF1, PAX5, RB1, PAR1 region (CRLF2, CSF2RA, IL3RA) , ETV6)
Target genes
To include hyperdiploidy, high hyperdiploidy, near haploidy, low hypodiploidy, Chr1p33, Chr21, copy number changes of IKZF1, CDKN2A, CDKN2B, BTG1, EBF1, PAX5, RB1, PAR1 region (CRLF2, CSF2RA, IL3RA) , ETV6
Test scope
Copy number variant detection to genomewide resolution
Test method/ technology
Panel
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.79
Test name
MRD BCR-ABL1 RT-qPCR rare
Target genes
BCR-ABL1 non-p190 & non-p210 transcripts
Test scope
Structural variant detection
Test method/ technology
QF-PCR or equivalent
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M91.80
Test name
TPMT
Target genes
TPMT
Test scope
Single Nucleotide Polymorphism/Small variant detection
Test method/ technology
Simple targeted mutation testing
Optimal Family Structure
n/a
Eligibility Criteria
Patient with a confirmed diagnosis of acute lymphoblastic leukaemia and proposed treatment involving purine analogue based drugs
Test code
M91.81
Test name
NUDT15
Target genes
NUDT15
Test scope
Single Nucleotide Polymorphism/Small variant detection
Test method/ technology
Simple targeted mutation testing
Optimal Family Structure
n/a
Eligibility Criteria
Patient with a confirmed diagnosis of acute lymphoblastic leukaemia and proposed treatment involving purine analogue based drugs
Commissioning group
n/a
Overlapping idications
n/a
Address for samples/request forms
North Thames GLH, Rare & Inherited Disease Genomic Laboratory
Specimen Reception, Level 5 Barclay House, 37 Queen Square,
London WC1N 3BH
Contact with queries
Supporting documents
n/a
Education resources
n/a
Service updates
n/a
Request form download
n/a
Consent record
See consent guidance in test request form
Sample requirements
See sample guidance in test request form