CYP2C19 resources

These resources are focused on CYP2C19 and considerations required for the safe and effective implementation of CYP2C19 testing at a local level.

We recommend that you start with the podcasts and/or the educational webinars before moving onto the resources centred on how to interpret a CYP2C19 pharmacogenetic report. Everyone’s learning needs are different, so you may want to take a different approach.

It should also be noted that any information on dosing should be read with caution as it may not reflect local/regional or national UK prescribing practices.

The resources below, especially the workshop materials can be used locally for department/clinical unit training.

Podcasts: Educational 5x bitesize episodes which are 10 to 15 minutes long

• Podcast

Education and training webinar

CYP2C19 testing within clinical practice: Focus on cardiomyopathy and stroke – North Thames GMS : North Thames GMS

Factsheets

• CYP2C19

CYP2C19 implementation resources

• CYP2C19 resources
  • Pathway and governance considerations for CYP2C19 testing

Interpreting CYP2C19 pharmacogenetic reports

• How to interpret a pharmacogenetic test report for clopidogrel prescribing on demand training
• Pharmacogenetic case studies and workshop materials

In-clinic resources

• Clopidogrel and CYP2C19 GeNotes

Variant interpretation – Please note guidance may not follow UK prescribing.

• Clopidogrel CPIC guideline link here
• Interactive CPIC guideline on pharmgkb.org (star alleles can be inputted)
• Also include link for app