Across our region, the NHS North Thames Genomic Medicine Service (NT GMS) is helping to strengthen access to a wide range of clinical trials by embedding genomics into routine care, supporting multidisciplinary decision‑making and creating the conditions for research to happen earlier and more equitably.
For example, the NT GMS has established itself as a leader in collaborating with pioneering cancer clinical trial teams, forging partnerships that accelerate access to novel therapies and transformative research. Over the next 10-years we aim to build on our collaborations to drive forward the next wave of cancer clinical trials.
Genomics built into cancer pathways
A core ambition of the NHS GMS is to ensure that genomic testing is fully embedded within end‑to‑end cancer pathways, rather than sitting alongside routine care.
Through the Cancer Genomics Clinical Function, patients across the country are offered comprehensive genomic analysis and molecular profiling where appropriate, supporting more precise diagnosis and treatment decisions. Crucially, this approach is designed to align routine cancer genomic testing with eligibility for clinical trials, helping clinicians consider research options at the right point in a patient’s journey.
By making genomics part of standard pathways, trial opportunities can be identified systematically and not through chance or referral to a small number of specialist centres.
“Genomics is a powerful enabler of cancer clinical trials because it can identify patients who are most likely to respond to a new treatment,” says Mike Hubank, Scientific Lead for the North Thames Genomic Medicine Service.
“Because of advances in genomic testing, we can now identify patients for clinical trials using the same tests we use for standard treatments, meaning efficiency for the NHS, and better trials access for patients. Clinical Research has become a normal part of treatment discussions, not an exception.”