Curated collections
Explore our themed educational resources and build your knowledge of genomics in healthcare
Whole Genome Sequencing
Whole Genome Sequencing (WGS) describes the sequencing of an individuals entire genome. WGS is most commonly thought of as being used in cases of rare disease; however it is also increasingly used in patients with cancer, where WGS of the tumour’s (somatic) genome can be undertaken.
WGS can be requested by clinicians using specific forms and via a clear consent process. This curated collection provides key training for clinicians hoping to learn more about the applications of WGS, as well as understanding the requesting process more.
More information about this topic can be found on the Genomics Education Programme website.
You can also watch our WGS animation on the North Thames Genomic Medicine Service YouTube channel (available in multiple languages).
What are the sample quality requirements for whole genome sequencing. (HB4).
What are the sample quality requirements for whole genome sequencing. (PB4).
On 14 July 2022 the North Thames Genomic Medicine Service (GMS) held an event showcasing how genomic medicine is transforming healthcare in our region.
Dr Jack Bartram is a Consultant Paediatric Haematologist at Great Ormond Street Hospital for Children. In this talk he explains the benefits of whole genome sequencing in paediatric haematology and how consolidating panel testing is enabling delivery of a new standard for care for diagnostics in paediatric blood cancers.
The Genomics Education Programme is delighted to present a special three-part educational programme on how to read the cancer genome, presented by Professor Serena Nik-Zainal.
The first part of the series focuses on the basics of cancer genomics, from raw sequence reads through to somatic mutations.
Professor Nik-Zainal is an NIHR research professor and an honorary consultant in clinical genetics. Professor Nik-Zainal is a celebrated leader in somatic cancer research and has spearheaded work into mutational signatures and their application to clinical practice.