Request / Find a Test Tool

The National Genomic Test Directories specify which genomic tests are commissioned by the NHS in England, to be delivered by Genomic Laboratory Hubs.

This tool allows clinical teams to search all of the genomic tests available to patients through the National Testing Directory. From here you can find out more details about each test and information about how to order them. These tests can only be ordered by clinical teams, if you are a patient looking to request a test please speak to your clinical team directly.

T Cell Non-Hodgkin Lymphoma

Clinical Indication ID & Name

M111

T Cell Non-Hodgkin Lymphoma

Test Group

Haematology

Specialties

Test code

M111.1

Test name

Multi-target NGS panel - small variant (RHOA, DNMT3A, IDH2, TET2)

Target genes

RHOA, DNMT3A, IDH2, TET2

Test scope

Small variant detection

Test method/ technology

Panel

Optimal Family Structure

n/a

Eligibility Criteria

Molecular assessment will aid diagnosis or management

Test code

M111.2

Test name

TCR gene rearrangement detection multiplex seq

Target genes

(TRA), TRB, TRG, TCRD

Test scope

Complex variant detection

Test method/ technology

Complex targeted mutation testing

Optimal Family Structure

n/a

Eligibility Criteria

Molecular assessment will aid diagnosis or management

Test code

M111.3

Test name

TCR gene rearrangement detection NGS

Target genes

(TRA), TRB, TRG, TCRD

Test scope

Complex variant detection

Test method/ technology

Panel

Optimal Family Structure

n/a

Eligibility Criteria

Molecular assessment will aid diagnosis or management

Test code

M111.4

Test name

TCR rearrangement FISH

Target genes

TRA, TRB, TRG

Test scope

Structural variant detection

Test method/ technology

FISH

Optimal Family Structure

n/a

Eligibility Criteria

Where demonstration of rearrangements of TCRA, TCRB & TCRG will aid with the diagnosis of a T cell lymphoma

Test code

M111.5

Test name

WGS Germline and Tumour

Target genes

All including burden / signature

Test scope

All variant types

Test method/ technology

WGS

Optimal Family Structure

n/a

Eligibility Criteria

For paediatric patients only

Test code

M111.6

Test name

Multi-target NGS panel - structural variant (TCR rearrangement)

Target genes

TRA, TRB, TRG

Test scope

Structural variant detection

Test method/ technology

Panel

Optimal Family Structure

n/a

Eligibility Criteria

Where demonstration of rearrangements of TCRA, TCRB & TCRG will aid with the diagnosis of a T cell lymphoma

Commissioning group

n/a

Overlapping idications

n/a

Address for samples/request forms

North Thames GLH, Rare & Inherited Disease Genomic Laboratory
Specimen Reception, Level 5 Barclay House, 37 Queen Square,
London WC1N 3BH

Contact with queries

rmh-tr.moleculardiagnostics@nhs.net

Supporting documents

Cancer WGS Clinician pack

Education resources

n/a

Service updates

n/a

Request form download

n/a

Consent record

See consent guidance in test request form

Sample requirements

See sample guidance in test request form