Request / Find a Test Tool

The National Genomic Test Directories specify which genomic tests are commissioned by the NHS in England, to be delivered by Genomic Laboratory Hubs.

This tool allows clinical teams to search all of the genomic tests available to patients through the National Testing Directory. From here you can find out more details about each test and information about how to order them. These tests can only be ordered by clinical teams, if you are a patient looking to request a test please speak to your clinical team directly.

Small Bowel Cancer

Clinical Indication ID & Name

M238

Small Bowel Cancer

Test Group

Solid Tumours (Adult)

Specialties

Test code

M238.1

Test name

MSI Testing

Target genes

N/A

Test scope

Microsatellite instability analysis

Test method/ technology

Microsatellite instability analysis

Optimal Family Structure

n/a

Eligibility Criteria

Known small bowel cancer, when MMR IHC not possible / not performed, as per NICE Guidelines for molecular testing to inform therapy choice. Delivery via pathology in some regions.

Test code

M238.2

Test name

DPYD hotspot

Target genes

DPYD

Test scope

Small variant detection

Test method/ technology

Simple targeted mutation testing

Optimal Family Structure

n/a

Eligibility Criteria

Patient planned to receive fluoropyrimidine treatment

Commissioning group

n/a

Overlapping idications

n/a

Address for samples/request forms

North Thames GLH, Rare & Inherited Disease Genomic Laboratory
Specimen Reception, Level 5 Barclay House, 37 Queen Square,
London WC1N 3BH

Contact with queries

rmh-tr.moleculardiagnostics@nhs.net

Supporting documents

Cancer WGS Clinician pack

Education resources

n/a

Service updates

n/a

Request form download

Solid Tumour Request Form

Consent record

See consent guidance in test request form

Sample requirements

See sample guidance in test request form