Request / Find a Test Tool

The National Genomic Test Directories specify which genomic tests are commissioned by the NHS in England, to be delivered by Genomic Laboratory Hubs.

This tool allows clinical teams to search all of the genomic tests available to patients through the National Testing Directory. From here you can find out more details about each test and information about how to order them. These tests can only be ordered by clinical teams, if you are a patient looking to request a test please speak to your clinical team directly.

Mantle Cell Lymphoma

Clinical Indication ID & Name

M102

Mantle Cell Lymphoma

Test Group

Haematology

Specialties

Test code

M102.1

Test name

t(11;14)(q13;q32) IGH-CCND1 FISH/RT-PCR

Target genes

IGH-CCND1

Test scope

Structural variant detection

Test method/ technology

FISH/Simple targeted mutation testing

Optimal Family Structure

n/a

Eligibility Criteria

Molecular assessment will aid diagnosis or management

Test code

M102.2

Test name

CCND1 rearrangement FISH

Target genes

CCND1

Test scope

Structural variant detection

Test method/ technology

FISH

Optimal Family Structure

n/a

Eligibility Criteria

Molecular assessment will aid diagnosis or management

Test code

M102.3

Test name

CCND2 rearrangement FISH

Target genes

CCND2

Test scope

Structural variant detection

Test method/ technology

FISH

Optimal Family Structure

n/a

Eligibility Criteria

Molecular assessment will aid diagnosis or management

Test code

M102.4

Test name

Multi-target NGS panel - structural variant (IGH-CCND1, other CCND1 rearrangements, CCND2)

Target genes

IGH-CCND1, CCND1, CCND2, CCND3

Test scope

Structural variant detection

Test method/ technology

Panel

Optimal Family Structure

n/a

Eligibility Criteria

Molecular assessment will aid diagnosis or management

Test code

M102.5

Test name

Multi-target NGS panel - small variant (TP53)

Target genes

TP53

Test scope

Small variant detection

Test method/ technology

Panel

Optimal Family Structure

n/a

Eligibility Criteria

Patient with MCL who are candidates for intensive treatment including autologous HSCT

Commissioning group

n/a

Overlapping idications

n/a

Address for samples/request forms

North Thames GLH, Rare & Inherited Disease Genomic Laboratory
Specimen Reception, Level 5 Barclay House, 37 Queen Square,
London WC1N 3BH

Contact with queries

rmh-tr.moleculardiagnostics@nhs.net

Supporting documents

Cancer WGS Clinician pack

Education resources

n/a

Service updates

n/a

Request form download

n/a

Consent record

See consent guidance in test request form

Sample requirements

See sample guidance in test request form