Clinical Indication ID & Name
Burkitt Lymphoma
Test Group
Haematology
Specialties
Test code
M96.1
Test name
MYC rearrangement FISH
Target genes
MYC
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M96.2
Test name
t(8:14)(q34:q32) IGH-MYC FISH/RT-PCR
Target genes
IGH-MYC
Test scope
Structural variant detection
Test method/ technology
FISH/Simple targeted mutation testing
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M96.3
Test name
t(8:22)(q24:q11) IGK-MYC FISH/RT-PCR
Target genes
IGK-MYC
Test scope
Structural variant detection
Test method/ technology
FISH/Simple targeted mutation testing
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M96.4
Test name
t(2:8)(p12:q24) IGL-MYC FISH/RT-PCR
Target genes
IGL-MYC
Test scope
Structural variant detection
Test method/ technology
FISH/Simple targeted mutation testing
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M96.5
Test name
BCL2 rearrangement FISH
Target genes
BCL2
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M96.6
Test name
BCL6 rearrangement FISH
Target genes
BCL6
Test scope
Structural variant detection
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Test code
M96.7
Test name
WGS Germline and Tumour
Target genes
All including burden / signature
Test scope
All variant types
Test method/ technology
WGS
Optimal Family Structure
n/a
Eligibility Criteria
For paediatric patients only
Test code
M96.8
Test name
Multi-target NGS panel - structural variant (IGH-MYC, IGK-MYC, IGL-MYC, other rearrangements of MYC, BCL2, BCL6)
Target genes
IGH-MYC, IGK-MYC, IGL-MYC, MYC, BCL2, BCL6
Test scope
Structural variant detection
Test method/ technology
Panel
Optimal Family Structure
n/a
Eligibility Criteria
Molecular assessment will aid diagnosis or management
Commissioning group
n/a
Overlapping idications
n/a
Address for samples/request forms
North Thames GLH, Rare & Inherited Disease Genomic Laboratory
Specimen Reception, Level 5 Barclay House, 37 Queen Square,
London WC1N 3BH
Contact with queries
Supporting documents
Cancer WGS Clinician pack
Education resources
n/a
Service updates
n/a
Request form download
n/a
Consent record
See consent guidance in test request form
Sample requirements
See sample guidance in test request form